Author

V. Marabitti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 5 Approach:experimental assay· 5 Organism:human· 5 Assay:DNA methylation· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Approach:wet-lab / biochemical assay· 2

Frequent Co-Authors

A. Franchitto· 5 shared P. Pichierri· 5 shared E. Malacaria· 2 shared G. M. Pugliese· 2 shared P. Valenzisi· 2 shared V. Palermo· 2 shared A. Minoprio· 1 shared A. Palma· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersCell Biology

A. Franchitto

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Author profile →

5 papers

Recent·Most cited

WRNIP1 prevents transcription-associated genomic instability

P. Valenzisi, V. Marabitti, P. Pichierri, A. Franchitto

This study identifies WRNIP1 as a factor that prevents transcription-associated genomic instability by resolving R-loop conflicts and limiting DNA damage.

bioRxiv · Jun 23, 2023Cell Biology

WRNIP1 PREVENTS G4/R-LOOP-ASSOCIATED GENOMIC INSTABILITY

P. Valenzisi, V. Marabitti, S. Petrai, F. R. Giardinelli, P. Pichierri, A. Franchitto

This study identifies WRNIP1's role in preventing DNA damage caused by G4/R-loop-associated transcription-replication conflicts by stabilizing FANCJ at G4 sites.

bioRxiv · Dec 17, 2022 · PreprintCell Biology

Checkpoint defects require WRNIP1 to counteract R-loop-associated genomic instability

A. Franchitto, V. Marabitti, G. Lillo, E. Malacaria, V. Palermo, P. Pichierri

The paper shows WRNIP1 stabilizes genome integrity by mediating ATM-dependent CHK1 phosphorylation and RAD51 ssDNA association in response to R-loop accumulation.

bioRxiv · Nov 29, 2019 · PreprintCancer Biology

Generation of inducible SMARCAL1 knock-down iPSC to model severe Schimke immune-osseous dysplasia reveals a link between replication stress and altered expression of master differentiation genes

G. M. Pugliese, F. Salaris, V. Palermo, V. Marabitti, N. Morina, A. Rosa, A. Franchitto, P. Pichierri

This study generates SMARCAL1 knock-down iPSCs to model Schimke immune-osseous dysplasia, revealing replication stress and altered gene expression as key factors in disease pathogenesis.

bioRxiv · Feb 10, 2019Cell Biology

Phosphorylation By CK2 Regulates MUS81/EME1 In Mitosis And After Replication Stress

A. Palma, G. M. Pugliese, I. Murfuni, V. Marabitti, E. Malacaria, S. Rinalducci, A. Minoprio, M. Sanchez, F. Mazzei, L. Zolla, A. Franchitto, P. Pichierri

This study shows CK2 phosphorylates MUS81 at Serine 87 in mitosis and under replication stress, promoting its interaction with SLX4 and affecting chromosome stability.

bioRxiv · Mar 7, 2018Cell Biology