Author

V. Muehlgrabner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:virus· 1

Frequent Co-Authors

J. B. Huppa· 3 shared R. Platzer· 2 shared A. Bergthaler· 1 shared A. Lercher· 1 shared A. Plach· 1 shared A. Popa· 1 shared A. Zoufaly· 1 shared B. Agerer· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

J. B. Huppa

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3 papers

Recent·Most cited

TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation

T. Peters, V. Muehlgrabner, R. M. H. Velasco Cardenas, R. Platzer, J. Gohring, B. Salzer, A. Plach, M. Hoehrhan, I. Doel-Perez, V. D. R. Goncalves, J. S. Farfan, M. Lehner, H. Stockinger, W. W. Schamel, K. Schober, , J. B. Huppa

This study shows TCR/CD3-based synthetic antigen receptors (TCC) have superior antigen sensitivity and activation fidelity compared to second-generation CARs.

bioRxiv · Mar 16, 2023 · PreprintImmunology

Strategies for the site-specific decoration of DNA origami nanostructures with functionally intact proteins

J. Hellmeier, R. Platzer, V. Muehlgrabner, M. C. Schneider, E. Kurz, G. J. Schuetz, J. B. Huppa, E. Sevcsik

This study evaluates strategies for site-specific decoration of DNA origami with functional proteins, finding that PNA-based conjugation best preserves protein function and stoichiometry.

bioRxiv · Jul 1, 2021Biophysics

SARS-CoV-2 escapes CD8 T cell surveillance via mutations in MHC-I restricted epitopes

B. Agerer, M. Koblischke, V. Gudipati, M. Smyth, A. Popa, J.-W. Genger, L. Endler, D. M. Florian, V. Muehlgrabner, A. Lercher, P. Gattinger, R. Torralba-Gombau, T. Penz, I. Fae, S. Wenda, , A. Bergthaler

The paper identifies mutations in SARS-CoV-2 that reduce MHC-I binding and CD8+ T cell recognition, suggesting escape from immune surveillance.

bioRxiv · Dec 18, 2020 · PreprintImmunology