Author

V. Niederlova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

O. Stepanek· 3 shared A. Drobek· 2 shared J. Michalik· 2 shared A. Moudra· 1 shared A. Neuwirth· 1 shared A. Prasai· 1 shared D. Cizkova· 1 shared H. Kozakova· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

O. Stepanek

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2

O. Tsyklauri, T. Chadimova, V. Niederlova, J. Kovarova, J. Michalik, I. Malatova, S. Janusova, O. Ivashchenko, H. Rossez, A. Drobek, H. Vecerova, V. Galati, M. Kovar, O. Stepanek

This study identifies Tregs suppressing KLRK1+ IL7R+ CD8+ effector T cells by limiting IL-2, which enhances autoimmunity and anti-tumor responses.

bioRxiv · Nov 10, 2021Immunology

Phenotypic and clonal stability of antigen-inexperienced memory-like T cells across the genetic background, hygienic status, and aging

A. Moudra, V. Niederlova, J. Novotny, L. Schmiedova, J. Kubovciak, T. Matejkova, A. Drobek, M. Pribikova, R. Stopkova, D. Cizkova, A. Neuwirth, J. Michalik, K. Krizova, T. Hudcovic, M. Kolar, , O. Stepanek

This study characterizes antigen-inexperienced memory-like T cells across genetic backgrounds, hygienic conditions, and aging, showing their clonal stability and distinct subsets defined by CD122 expression.

bioRxiv · Sep 1, 2020Immunology

The BBSome assembly is spatially controlled by BBS1 and BBS4 in human cells

A. Prasai, M. Schmidt Cernohorska, K. Ruppova, V. Niederlova, M. Andelova, P. Draber, O. Stepanek, M. Huranova

The paper investigates BBSome assembly in human cells, showing that BBS4 nucleates pre-BBSome at pericentriolar satellites and BBS1 mediates its translocation to the ciliary base.

bioRxiv · Mar 20, 2020Cell Biology