Author

J. Kovarova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:Drosophila· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Bajgar· 1 shared A. Drobek· 1 shared A. Zikova· 1 shared D. Horn· 1 shared G. Krejcova· 1 shared H. Rossez· 1 shared H. Vecerova· 1 shared H. Zemanova· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

A. Bajgar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The bloodstream form of Trypanosoma brucei displays non-canonical gluconeogenesis

J. Kovarova, M. Moos, M. P. Barrett, D. Horn, A. Zikova

This study identifies a non-canonical gluconeogenesis pathway in Trypanosoma brucei by showing sustained metabolic flux despite gene knockouts, suggesting a unique enzyme is involved.

bioRxiv · Apr 6, 2023 · PreprintBiochemistry

Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2

O. Tsyklauri, T. Chadimova, V. Niederlova, J. Kovarova, J. Michalik, I. Malatova, S. Janusova, O. Ivashchenko, H. Rossez, A. Drobek, H. Vecerova, V. Galati, M. Kovar, O. Stepanek

This study identifies Tregs suppressing KLRK1+ IL7R+ CD8+ effector T cells by limiting IL-2, which enhances autoimmunity and anti-tumor responses.

bioRxiv · Nov 10, 2021Immunology

Macrophage-derived insulin/IGF antagonist ImpL2 regulates systemic metabolism for mounting an effective acute immune response in Drosophila

G. Krejcova, A. Bajgar, P. Nedbalova, J. Kovarova, N. Kamps-Hughes, H. Zemanova, L. Strych, T. Dolezal

This study shows that Drosophila macrophages release ImpL2, an insulin/IGF antagonist, to regulate systemic metabolism during acute immune responses, but this becomes maladaptive in chronic infections.

bioRxiv · Sep 24, 2020 · PreprintImmunology