Author

V. Tergaonkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Aiderus· 1 shared A. H. P. Loh· 1 shared A. H.-H. Wong· 1 shared A. W.-C. Koh· 1 shared A. Y.-F. Chung· 1 shared B. K. P. Goh· 1 shared B. Ku· 1 shared C. A. Scott· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperCancer Biology

A. Aiderus

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multi-region spatial transcriptome analysis reveals cellular networks and pathways associated with hepatocellular carcinoma recurrence

A. Aiderus, P. V. Seshachalam, K. Idzham, M. Caldez, R. Shanmugam, I. N. Sari, D. H. H. Ying, S. L. Chong, K. Sekar, S. C. Chew, G. B. Chen, A. Y.-F. Chung, P. C. Cheow, J. H. Kam, A. W.-C. Koh, , P. K. H. Chow

This study uses spatial transcriptomics to analyze HCC tumor sectors and identifies endothelial cell enrichment and ligand-receptor interactions linked to disease recurrence.

bioRxiv · Jul 26, 2023 · PreprintCancer Biology

BRD4 isoforms have distinct roles in tumor progression and metastasis in embryonal rhabdomyosarcoma

R. Taneja, D. Das, J. Y. Leung, V. Tergaonkar, A. H. P. Loh, C.-M. Chiang

This study shows BRD4-L and BRD4-S isoforms have distinct roles in embryonal rhabdomyosarcoma, with BRD4-L promoting tumor growth and BRD4-S preventing metastasis.

bioRxiv · Jul 26, 2023 · PreprintCancer Biology

In vitro cytokine expression analysis by droplet microfluidics

A. H.-H. Wong, S. C. Akincilar, J. Y. H. Chua, D. d. K. Chanthira Morgan, D. Hei, V. Tergaonkar

The paper demonstrates the use of droplet microfluidics for in vitro cytokine expression analysis using engineered breast cancer cells, showing recapitulation of cellular response without absolute quantification.

bioRxiv · Dec 28, 2021 · PreprintCancer Biology

High-dose drug heat map based on organoid array chip for drug selection with high safety and efficacy

S.-Y. Lee, Y. Teng, M. Son, B. Ku, H. S. Moon, V. Tergaonkar, P. K.-H. Chow, D. W. Lee, D.-H. Nam

The paper develops an organoid array chip to test drug safety and efficacy using high-dose drug heat maps, identifying four compounds with high efficacy and low toxicity against GBM cells.

bioRxiv · May 11, 2021 · PreprintCancer Biology

Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

J. Ma, C. A. Scott, Y. N. Ho, K. S. Marsay, C. Zhang, C. K. J. Teow, S. S. Ng, W. Zhang, V. Tergaonkar, L. J. Partridge, S. Roy, E. Amaya, T. J. Carney

This study shows that Matriptase promotes tissue damage responses by activating Gq signaling, leading to RSK and DUOX activation, which disrupts epithelial junctions and contributes to inflammation and carcinoma.

bioRxiv · Jan 21, 2021 · PreprintCell Biology