Author

L. J. Partridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

L. R. Green· 2 shared L. Urwin· 2 shared P. N. Monk· 2 shared B. Ciani· 1 shared C. A. Scott· 1 shared C. E. Turner· 1 shared C. K. J. Teow· 1 shared C. Zhang· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

L. R. Green

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

CD9 co-operation with syndecan-1 is required for a major staphylococcal adhesion pathway

L. R. Green, R. Issa, F. Albaldi, L. Urwin, H. Khalid, C. E. Turner, B. Ciani, L. J. Partridge, P. N. Monk

This study shows CD9 and syndecan-1 cooperate for staphylococcal adhesion, with fibronectin also playing a role, and suggests CD9-targeted therapies could block bacterial entry.

bioRxiv · Jan 17, 2023Microbiology

ACE2-independent interaction of SARS-CoV-2 spike protein to human epithelial cells can be inhibited by unfractionated heparin

L. J. Partridge, L. Urwin, M. J. Nicklin, D. C. James, L. R. Green, P. N. Monk

This paper shows that SARS-CoV-2 spike protein can interact with human cells without ACE2 and that unfractionated heparin inhibits this interaction.

Cells · Jun 7, 2021Peer-reviewedMicrobiology

Matriptase generates a tissue damage response via promoting Gq signalling, leading to RSK and DUOX activation

J. Ma, C. A. Scott, Y. N. Ho, K. S. Marsay, C. Zhang, C. K. J. Teow, S. S. Ng, W. Zhang, V. Tergaonkar, L. J. Partridge, S. Roy, E. Amaya, T. J. Carney

This study shows that Matriptase promotes tissue damage responses by activating Gq signaling, leading to RSK and DUOX activation, which disrupts epithelial junctions and contributes to inflammation and carcinoma.

bioRxiv · Jan 21, 2021 · PreprintCell Biology