Author
UPMC Hillman Cancer Center
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Matthew A. Schaich, Tyler Weaver, Jennifer A Rakowski…·Bennett Van Houten
This study investigates how PARP1 binds to DNA breaks and chromatin, revealing that nucleosome unwrapping and allostery influence its affinity and binding dynamics.
Matthew A. Schaich, Brittani L Schnable, Namrata Kumar…·Bennett Van Houten
SMADNE characterizes DNA-binding protein dynamics using single-molecule analysis from nuclear extracts, revealing binding lifetimes, diffusion, and complex assembly kinetics.
Ryan P. Barnes, Mariarosaria De Rosa, Sanjana A. Thosar…·Patricia Lynn Opresko
This study shows that telomeric 8-oxoguanine induces premature senescence without telomere shortening by causing replication stress and dysfunction.