Resolving cell lineages and gene functions in the developing mouse gastrointestinal tract using in utero transduction
Ziwei Liu, Krishnanand Padmanabhan, Jingyan He, Katrin Mangold, Bettina Semsch, Jia Sun, Viktoria Knoflach, Sarantis Giatrellis, Johan Lorentz, Khachatur Dallakyan, Christian Göritz, Emma Rachel Andersson, Ulrika Marklund
This study uses in utero lentiviral transduction to resolve clonal relationships and gene functions in developing mouse gut lineages, revealing distinct developmental patterns in mesenchyme and enteric nervous system.
Proceedings of the National Academy of Sciences · Sep 9, 2026Peer-reviewedDevelopmental Biology