Katrin Mangold

Resolving cell lineages and gene functions in the developing mouse gastrointestinal tract using in utero transduction

This study uses in utero lentiviral transduction to resolve clonal relationships and gene functions in developing mouse gut lineages, revealing distinct developmental patterns in mesenchyme and enteric nervous system.

Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases

The paper profiles clonal landscapes in mouse embryos to reveal spatial modulators of clonal fate biases using single-cell lineage tracing and clone2vec.

Sex differences and risk factors for bleeding in Alagille syndrome

The paper identifies sex differences in bleeding risk and explores non-invasive vascular analysis in Alagille syndrome using mouse models and retinography.

Neural Plate Targeting by in Utero NanoinjEction (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

The paper introduces NEPTUNE, an in utero nanoinjection method to study gene function in mouse embryos, and shows that Sptbn2 silencing causes neural tube defects and embryo resorption.