Author

W. Bahnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 3 Assay:proteomics· 3 Organism:mouse· 2

Frequent Co-Authors

P. Nordenfelt· 4 shared S. Wrighton· 4 shared H. Khakzad· 3 shared L. Happonen· 3 shared O. Andre· 3 shared D. Tang· 2 shared E. Bratanis· 2 shared J. Malmström· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersImmunology

P. Nordenfelt

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The increased hinge flexibility of an IgG1-IgG3 hybrid monoclonal enhances Fc-mediated protection against group A streptococci

A. Izadi, Y. Karami, E. Bratanis, S. Wrighton, H. Khakzad, M. Nyblom, B. Olofsson, L. Happonen, D. Tang, M. Nilges, J. Malmström, W. Bahnan, O. Shannon, L. Malmström, P. Nordenfelt

This study shows that increasing Fc flexibility in an IgG1-IgG3 hybrid monoclonal antibody enhances opsonic function and protection against group A streptococci.

bioRxiv · Oct 14, 2023 · PreprintImmunology

Group A streptococci induce high-affinity M protein-fibronectin interaction when specific human antibodies are bound

S. Wrighton, V. Kumra Ahnlide, O. Andre, W. Bahnan, P. Nordenfelt

The paper shows that human antibodies can enhance the Fn-binding affinity of GAS M proteins by targeting a conserved region, allowing bacteria to bind Fn more efficiently without producing additional proteins.

bioRxiv · May 4, 2022 · PreprintImmunology

Opsonization by non-neutralizing antibodies can confer protection to SARS-CoV-2 despite Spike-dependent modulation of phagocytosis

W. Bahnan, S. Wrighton, M. Sundwall, A. Bläckberg, O. Larsson, U. Höglund, H. Khakzad, M. Godzwon, M. Walle, E. Elder, L. Happonen, O. Andre, J. Kumra Ahnlide, T. Hellmark, V. Wendel-Hansen, , P. Nordenfelt

This study shows that non-neutralizing Spike-specific antibodies can enhance phagocytosis of SARS-CoV-2 by monocytes, potentially offering protection despite not neutralizing the virus.

bioRxiv · Oct 14, 2021Immunology

A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein protects against infection

W. Bahnan, L. Happonen, H. Khakzad, V. Kumra Ahnlide, T. de Neergaard, S. Wrighton, O. Andre, E. Bratanis, D. Tang, T. Hellmark, L. Bjorck, O. Shannon, L. Malmstrom, J. Malmstrom, P. Nordenfelt

The paper describes a human monoclonal antibody that binds two distinct epitopes on streptococcal M protein via a bivalent dual-Fab cis mode, providing protection against infection.

bioRxiv · Mar 1, 2021 · PreprintImmunology

The eIF2α Kinase Heme Regulated Inhibitor (HRI) Protects The Host From Infection By Regulating Intracellular Pathogen Trafficking

W. Bahnan, J. Boucher, P. Gayle, N. Shrestha, M. Rosen, B. Aktas, B. Adkins, A. Ager, W. Khan, K. Schesser

This study shows that HRI protects against Listeria monocytogenes infection by restricting pathogen trafficking and antigen presentation.

bioRxiv · May 26, 2017Immunology