Author

W. E. Reintsch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

B. Vanderperre· 2 shared E. A. Fon· 2 shared I. Shlaifer· 2 shared W. Luo· 2 shared A. Bayati· 1 shared A. Muraleedharan· 1 shared C. E. Zorca· 1 shared C. Han· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

B. Vanderperre

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans

B. Vanderperre, A. Muraleedharan, M.-F. Dorion, F. Larroquette, E. Del Cid Pellitero, N. Rajakulendran, C. X.- Q. Chen, R. Lariviere, C. Michaud-Tardif, R. Chidiac, D. Lipuma, G. Macleod, R. Thomas, Z. Wang, W. E. Reintsch, , E. A. Fon

This study uses CRISPR/Cas9 screening to identify genes regulating α-synuclein fibril uptake via heparan sulfate proteoglycans, revealing SLC39A9 and C3orf58 as key modulators.

bioRxiv · Sep 29, 2023 · PreprintCell Biology

Rapid macropinocytic transfer of α-synuclein to lysosomes

A. Bayati, E. Banks, C. Han, W. Luo, W. E. Reintsch, C. E. Zorca, I. Shlaifer, E. D. C. Pellitero, B. Vanderperre, H. M. McBride, E. A. Fon, T. A. Durcan, P. S. McPherson

This study shows alpha-synuclein fibrils are rapidly internalized via macropinocytosis and directed to lysosomes, with some transferred to neighboring cells.

bioRxiv · Jan 6, 2022Cell Biology