MyD88-Syk axis is a critical determinant for inflammatory response in macrophages
Y.-S. Yi, J. H. Kim, W. S. Yang, E. Kim, D. Jeong, J. G. Park, N. Aziz, S. Kim, N. Parameswaran, J. Y. Cho
This study shows that the MyD88-Syk axis drives inflammatory responses in macrophages by promoting ROS/RNS generation and phagocytic activity through Src, F-actin, and Rac1.
bioRxiv · Nov 15, 2019 · PreprintImmunology