Tao Xu

Stimulus overlap confounds generalization in EEG foundation-model benchmarks

The paper evaluates how stimulus overlap affects generalization in EEG foundation models, finding that it significantly improves decoding accuracy and accounts for most seen-stimulus performance.

Stage-adaptive integration of polydopamine promotes hPSC-derived alveolar organoids differentiation and maturation

This study shows that stage-adaptive integration of polydopamine coatings and nanoparticles enhances the maturation and secretory function of hPSC-derived alveolar organoids.

CREG1 restricts ALV-J replication via the mitochondrial dysfunction-driven activation of innate immunity and apoptosis

This study identifies CREG1 as a host factor that restricts ALV-J replication by inducing mitochondrial dysfunction and activating innate immunity and apoptosis.

TIP-seq: A Single-cell Multiomics Approach for Simultaneous Transcriptome and Intracellular Protein Profiling

TIP-seq enables simultaneous transcriptome and protein profiling in single cells, revealing immune checkpoint interactions and tumor microenvironment dynamics in NSCLC.

hPSC-Derived Distal Lung Organoids Reveal Respiratory Airway Secretory Cells Acting as Immune Sentinels in Human Distal Airways

This study uses hPSC-derived distal lung organoids to identify RAS cells as immune sentinels in human distal airways, revealing their roles in viral, bacterial responses, and COPD.

Massively parallel interrogation of human functional variants modulating cancer immunosurveillance

The paper identifies functional mutations affecting PD-L1 and HLA-I expression using a large-scale CRISPR screen, revealing clinically relevant variants that influence immunotherapy response.

A Universal Language for Finding Mass Spectrometry Data Patterns

MassQL, an open-source query language, lets users search raw mass spectrometry data from any vendor for isotope, fragmentation and neutral-loss patterns, from one file to entire public repositories.

Identification of a Novel Gene argJ involved in Arginine Biosynthesis Critical for Persister Formation in Staphylococcus aureus

This study identifies argJ, a gene involved in arginine biosynthesis, as critical for persister formation in S. aureus, with implications for developing new treatments for persistent infections.