Wenzhong Yang

TPM4 condensates glycolytic enzymes to fuel actin reorganization under hyperosmotic stress

The paper shows that TPM4 forms condensates with glycolytic enzymes under hyperosmotic stress, linking actin reorganization to metabolic activity.

Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer's disease model mice

Treatment with eEF2K inhibitors and genetic eEF2K knockout improved cognitive deficits in Alzheimer's disease model mice.

Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease

This study shows that reducing eIF2-P in Alzheimer's mouse models improves protein synthesis, synaptic plasticity, and memory.

Genome sequencing combining prenatal ultrasound in the evaluation of fetal CNS structural anomalies

This study evaluates genome sequencing for diagnosing fetal CNS structural anomalies, finding a 38.9% overall diagnostic yield and higher rates in specific malformations.