Author

Wuhong Pei

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Shawn Michael BurgessiD· 3 shared Alice YoungiD· 1 shared Beatrice B. Barnabas· 1 shared Brian SchmidtiD· 1 shared Casandra Montemayor· 1 shared Catherine A. Masiello· 1 shared Chanthra Scharer· 1 shared Christina Sison· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersDevelopmental Biology

Shawn Michael BurgessORCID

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Author profile →

3 papers

Recent·Most cited

Tnfrsf10 Signaling is Required to Maintain the Stem Cell Niche in the Zebrafish Lateral Line

Chunxin Fan, Xiaoyi Yuan, Jian Wang, Wuhong Pei, Hongfei Zheng, Xinyu Zhang, Shawn Michael Burgess

This study identifies tnfrsfa as essential for maintaining the stem cell niche in zebrafish neuromasts and supporting hair cell regeneration through NF-κB signaling and Sox2 expression.

bioRxiv · Apr 18, 2025 · PreprintDevelopmental Biology

Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

Li Wang, Matteo Astone, Sk. Kayum Alam, Zhu Zhu, Wuhong Pei, David A. Frank, Shawn Michael Burgess, Luke H. Hoeppner

This study shows that inhibiting STAT3 reduces VEGF-induced vascular permeability in zebrafish, mice, and human endothelium, suggesting a therapeutic target for diseases involving vascular leakage.

Disease Models & Mechanisms · Sep 20, 2021Peer-reviewedMolecular Biology

A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

Wuhong Pei, Lisha Xu, Zelin Chen, Claire C. Slevin, Kade P. Pettie, Stephen Wincovitch, NISC Comparative Sequencing Program, Beatrice B. Barnabas, Sean Black, Gerard G. Bouffard, Shelise Y. Brooks, Holly Coleman, Lyudmila Dekhtyar, Xiaobin Guan, Joel Han, , Shawn Michael Burgess

The paper identifies gemin3 as a regeneration-essential gene in zebrafish and shows smn1, gemin3, and gemin5 inhibit the ErbB pathway to promote cell proliferation during tissue regeneration.

npj Regenerative Medicine · Mar 25, 2020Peer-reviewedGenetics