Sk. Kayum Alam

This study shows that primary cilia formation contributes to resistance to osimertinib in EGFR-mutated NSCLC by promoting sodium influx and HDAC6 inactivity, and that targeting ciliogenesis can reverse resistance.

This study shows that dopamine D2 receptor agonists reduce angiogenesis and inhibit chemotherapy-refractory small cell lung cancer progression by targeting tumour-associated endothelial cells.

This study establishes a hairless mouse model of radiation dermatitis that mimics human disease, showing severe skin injury and specific histopathological markers for preclinical research.

This study shows that inhibiting STAT3 reduces VEGF-induced vascular permeability in zebrafish, mice, and human endothelium, suggesting a therapeutic target for diseases involving vascular leakage.

This study shows that VEGF signaling is activated by UV exposure and that inhibiting it can prevent sunburn symptoms in mice, suggesting a new therapeutic approach for UV-induced skin damage.