Author

X. Pechuan-Jorge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

A. A. Lo· 2 shared A. Wallace· 2 shared C. Havnar· 2 shared D. Oreper· 2 shared N. Lounsbury· 2 shared A. Ashkenazi· 1 shared C. J. Gaspar· 1 shared D. Kan· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. A. Lo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growth

I. Zuazo-Gaztelu, D. Lawrence, I. Oikonomidi, S. Marsters, X. Pechuan-Jorge, C. J. Gaspar, D. Kan, E. Segal, K. Clark, M. Beresini, M.-G. Braun, J. Rudolph, Z. Modrusan, M. Choi, W. Sandoval, , A. Ashkenazi

This study identifies a nonenzymatic role of IRE1 in cancer cell cycle progression and tumor growth, independent of its kinase-RNase activity.

bioRxiv · Nov 22, 2023Cancer Biology

Origins and timing of emerging lesions in advanced renal cell carcinoma

A. Wallace, S. Porten, A. A. Lo, D. Oreper, N. Lounsbury, C. Havnar, X. Pechuan-Jorge, O. Zill, M. Meng

This study uses multi-region sequencing to analyze the origins and timing of tumor lesions in advanced renal cell carcinoma, finding that metastases often emerge early and VTT forms later through inflammatory processes.

bioRxiv · Jun 27, 2021Cancer Biology

Indication-specific tumor evolution and its impact on neoantigen targeting and biomarkers for individualized cancer immunotherapies

A. A. Lo, A. Wallace, D. Oreper, N. Lounsbury, C. Havnar, X. Pechuan-Jorge, T. D. Wu, R. Bourgon, R. Jones, K. Krogh, G.-Y. Yang, O. A. Zill

The paper analyzes tumor evolution across cancer types to identify factors affecting neoantigen targeting in immunotherapy.

bioRxiv · Mar 15, 2021Cancer Biology