Evolutionarily Conserved and Divergent Mechanisms of Dual Ca2+ Sensors in Synaptic Vesicle Exocytosis
Lei Li, Jiafan Wang, Jingyao Xia, Xiaochun Yu, Jiayi Hu, Qinrong Zhang, Janet E. Richmond, Haowen Liu, Zhitao Hu
This study investigates how SNT-1 and SNT-3 mediate fast and slow neurotransmitter release in C. elegans by analyzing their interactions with SNARE complexes and polybasic motifs.
Proceedings of the National Academy of Sciences · Jun 18, 2026Peer-reviewedNeuroscience