Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats
Xiaoli Li, Xuejiao Jin, Sushma Sharma, Xiaojing Liu, Jiaxin Zhang, Yan-Ling Niu, Jiani Li, Zhen Li, Jingjing Zhang, Qinhong Cao, Wenya Hou, Li‐Lin Du, Beidong Liu, Huiqiang Lou
The paper identifies Mck1 as a key S-phase checkpoint effector that regulates dNTP homeostasis by modulating RNR and HUG1 expression in response to replication threats.
PLoS Genetics · Aug 5, 2019Peer-reviewedMolecular Biology