Transcription-independent hold of the G1/S transition is exploited to cope with DNA replication stress
Yue Jin, Guoqing lan, Jiaxin Zhang, Haoyuan Sun, Xin Li, Qinhong Cao, Chao Tang, Xiaojing Yang, Huiqiang Lou, Wenya Hou
The paper shows that overexpression of WHI7 bypasses the need for Mec1 and Rad53 in Saccharomyces cerevisiae, revealing a transcription-independent role in delaying G1/S transition during replication stress.
bioRxiv · Nov 10, 2022 · PreprintMolecular Biology