Author

Xiaoyang Zhang

Primary ORCID profile (0000-0002-0031-0290 · 4 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Xiaoyang ZhangiD4 papers · University of Utah

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bradley R. CairnsiD· 1 shared Craig A. Strathdee· 1 shared David Y. Takeda· 1 shared Ji-Heui SeoiD· 1 shared Jiao LiiD· 1 shared Jinxiu Li· 1 shared John G. DoenchiD· 1 shared Justin H. HwangiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Bradley R. CairnsORCID

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2 papers

Recent·Most cited

SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription

Jinxiu Li, Li Li, Kyllie Smith-Fry, Zaki F. Wilmot, Lara Carroll, Linda Morrison, Xinyi Ge, Mary Nelson, Lesley A. Hill, Xiaoyang Zhang, Torsten O. Nielsen, Martin Hirst, T. Michael Underhill, Bradley R. Cairns, Kevin B. Jones

This paper shows SS18::SSX fusion protein alters BAF chromatin remodeler distribution, leading to transcriptional activation and repression by changing histone modifications at regulatory regions.

bioRxiv · May 14, 2024 · PreprintCancer Biology

A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer

Stephen Tang, Nebiyou Y. Metaferia, Marina F. Nogueira, Maya K. Gelbard, Sarah Abou Alaiwi, Ji-Heui Seo, Justin H. Hwang, Craig A. Strathdee, Sylvan C. Baca, Jiao Li, Shatha AbuHammad, Xiaoyang Zhang, John G. Doench, William C. Hahn, David Y. Takeda, , Srinivas R. Viswanathan

This study identifies PRMT1 as a critical regulator of AR signaling in prostate cancer through genome-scale CRISPR screening and shows its potential as a therapeutic target.

Cell Reports · Feb 1, 2022Peer-reviewedCancer Biology