Author

Jinxiu Li

University of Utah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Kevin B. JonesiD· 3 shared Bradley Robert CairnsiD· 2 shared Kyllie Smith-Fry· 2 shared Lesley A. HilliD· 2 shared T. Michael UnderhilliD· 2 shared Torsten O. NielseniD· 2 shared Afroditi SotiriouiD· 1 shared Ana BanitoiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Kevin B. JonesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BAF complex-independent gene activation by SS18::SSX

Afroditi Sotiriou, Jinxiu Li, Sanya Middha, Jake A. Ward, Selina Troester, Lianghao Mao, Martin Schneider, Dario L. Frey, Eliza C. Wray, Sara Bocedi, Kyllie Smith-Fry, Linda C. Morrison, Lara S. Carroll, Mihaly Badonyi, Joseph A. Marsh, , Ana Banito

This study shows that SS18::SSX can drive transcription independently of BAF complex interaction and relies on EP300 for gene activation, suggesting new therapeutic targets for synovial sarcoma.

bioRxiv · Jan 27, 2026 · PreprintCancer Biology

Cell-of-origin epigenome underlies SS18::SSX-mediated transformation

Lesley A. Hill, R. Wilder Scott, Lauren A. Martin, Martin Arostegui, George Davenport, Marcos Vemon, Jakob Hofvander, Xue Qi Wang, Jinxiu Li, Torsten O. Nielsen, Kevin B. Jones, Martin Hirst, T. Michael Underhill

This study identifies the cell-of-origin of synovial sarcoma as a rare fibroblastic population and shows that SS18::SSX induces an embryonic-like mesenchymal stem cell phenotype.

bioRxiv · May 15, 2024Cancer Biology

SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription

Jinxiu Li, Li Li, Kyllie Smith-Fry, Zaki F. Wilmot, Lara Carroll, Linda Morrison, Xinyi Ge, Mary Nelson, Lesley A. Hill, Xiaoyang Zhang, Torsten O. Nielsen, Martin Hirst, T. Michael Underhill, Bradley R. Cairns, Kevin B. Jones

This paper shows SS18::SSX fusion protein alters BAF chromatin remodeler distribution, leading to transcriptional activation and repression by changing histone modifications at regulatory regions.

bioRxiv · May 14, 2024 · PreprintCancer Biology