N153-linked glycans on envelope protein protect orthoflaviviruses from antibody-mediated clearance
Donald Heng Rong Ting, Jan K. Marzinek, Corrine Wan, Palur Venkata Raghuvamsi, Fakhriedzwan Idris, Eunice Tze Xin Tan, Wei Teng Clara Koh, Xin Ni Lim, Tun-Linn Thein, Cheer Vee Lim, Chin Huan Ng, Theresa SC Buckley, Ian Walsh, Paul A. MacAry, Yee Sin Leo, , Sylvie Alonso
This study shows that N153-linked glycans on dengue virus envelope protein help evade antibody-mediated clearance, with implications for immune evasion in related flaviviruses.
bioRxiv · Feb 20, 2025 · PreprintMicrobiology