Author

Xin Xing

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron Watkins JamesiD· 1 shared Alexander BirbrairiD· 1 shared Ankit UniyaliD· 1 shared Aziguli Tulamaiti· 1 shared Benjamin LéviiD· 1 shared Carol D. MorrisiD· 1 shared Devadutta Balaji· 1 shared Dong-Xue Li· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Aaron Watkins JamesORCID

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2 papers

Recent·Most cited

Neural Arming Niche in Tumor-Draining Lymph Nodes Programs CD8⁺T Cell Cytotoxicity via GZMB Norepinephrinylation

Yang Yan, Xueli Zhang, Aziguli Tulamaiti, Shu-Yu Xiao, Yun-Zhen Qian, Jiamei Luo, Guang-Hong Su, Rui Lu, Junjie Wang, Hong-Tai Ma, Xiaqing Li, Wen-Tao Shi, Yuan-Xin Hong, Hou Jing-li, Li-Peng Hu, , Zhi-Gang Zhang

The paper shows that sympathetic norepinephrine in tumor-draining lymph nodes modifies GZMB in CD8 T cells to enhance cytotoxicity and improve tumor control.

bioRxiv · Feb 26, 2026 · PreprintCancer Biology

TrkA+ sensory neurons regulate osteosarcoma proliferation and vascularization to promote disease progression

Sowmya Ramesh, Qizhi Qin, Zhao Li, Masnsen Cherief, Lingke Zhong, Mary Archer, Xin Xing, Neelima Thottappillil, Devadutta Balaji, Sam S. Bae, Mario A. Gomez-Salazar, Mingxin Xu, Manyu Zhu, Ankit Uniyal, Leslie Chang, , Aaron Watkins James

This study shows that TrkA+ sensory neurons promote osteosarcoma progression by enhancing tumor growth, vascularization, and metastasis, and that inhibiting these neurons reduces disease severity and improves survival.

Proceedings of the National Academy of Sciences · Oct 21, 2025Peer-reviewedCancer Biology