Author

Xue Lu

The University of Queensland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Anthony T. PapenfussiD· 1 shared Binny JaradiiD· 1 shared Cassandra J. VandenbergiD· 1 shared Clare L. ScottiD· 1 shared Franziska GeissleriD· 1 shared Jacinta L. SimmonsiD· 1 shared Joep Vissers· 1 shared John V. PearsoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anthony T. PapenfussORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Genomic alterations enable BRCA1 methylation loss and promoter bypass to drive resistance in high-grade serous ovarian cancer

Longyun Xu, Ksenija Nesic, Sally Beard, Jacinta L. Simmons, Xue Lu, Cassandra J. Vandenberg, Sharon M. Hoyte, Binny Jaradi, Ratana Lim, Franziska Geissler, Stacey L. Edwards, Joep Vissers, Anthony T. Papenfuss, Sean Michael Grimmond, John V. Pearson, , Olga Kondrashova

This study identifies genomic mechanisms enabling BRCA1 methylation loss and promoter bypass in ovarian cancer, leading to PARP inhibitor resistance.

bioRxiv · Jul 30, 2026 · PreprintCancer Biology