Author

A. C. Hsieh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. A. Germanos· 1 shared A. G. Sowalsky· 1 shared A. Long· 1 shared A. T. Ku· 1 shared A. Wong· 1 shared B. M. Faltas· 1 shared C. M. Ghajar· 1 shared E. T. Goddard· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. A. Germanos

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2 papers

Recent·Most cited

Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations

S. Li, A. Wong, H. Sun, V. Bhatia, G. Javier, S. Jana, R. B. Mongomery, J. L. Wright, H.-M. Lam, A. C. Hsieh, B. M. Faltas, M. C. Haffner, J. K. Lee

This paper introduces a combinatorial genetic strategy to generate diverse cancer models and uses single-cell sequencing to identify polygenic drivers of cancer phenotypes.

bioRxiv · Apr 12, 2023 · PreprintCancer Biology

Defining cellular population dynamics at single cell resolution during prostate cancer progression

A. A. Germanos, S. Arora, Y. Zheng, E. T. Goddard, I. M. Coleman, A. T. Ku, S. Wilkinson, R. A. Amezquita, M. Zager, A. Long, Y. C. Yang, J. H. Bielas, R. Gottardo, C. M. Ghajar, P. S. Nelson, , A. C. Hsieh

This study examines prostate cancer progression at single-cell resolution, identifying castration-resistant luminal cells and their role in treatment resistance and tumor heterogeneity.

bioRxiv · Mar 2, 2022Cancer Biology