Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
F. Yue, A. T. Ku, P. Stevens, M. Michalski, W. Jiang, J. Tu, Z. Shi, Y. Dou, Y. Wang, X.-H. Feng, G. Hostetter, X. Wu, S. Huang, N. Shroyer, B. Zhang, , Y. Li
The paper shows that ZNRF3/RNF43 ubiquitinates and degrades EGFR, and their loss increases EGFR signaling, promoting cancer growth.
bioRxiv · Jan 10, 2024Cancer Biology
K. L. Morel, A. A. Hamid, B. G. Falcon, J. N. Singh, S. Linder, A. M. Bergman, H. G. van der Poel, I. Hofland, E. M. Bekers, S. Trostel, S. Wilkinson, A. T. Ku, D. L. Burkhart, M. Kim, J. Kim, , L. Ellis
This study shows that loss of ZFP36 promotes NF-κB activation and phenotypic plasticity in prostate cancer, leading to aggressive disease and castration resistance, which can be reversed by NF-κB inhibition.
bioRxiv · Aug 5, 2022 · PreprintCancer Biology
S. Agarwal, L. Fang, K. McGowen, J. Yin, J. Bowman, A. N. Alilin, A. T. Ku, E. Corey, M. Roudier, L. True, R. Dumpit, I. Coleman, J. Lee, P. S. Nelson, B. J. Capaldo, , K. Kelly
This study identifies biomarkers beyond B7H3 expression that predict response to a B7H3-ADC in metastatic prostate cancer models, improving therapeutic efficacy.
bioRxiv · Apr 19, 2022 · PreprintCancer Biology
M. L. Beshiri, B. J. Capaldo, R. Lake, A. T. Ku, D. Burner, C. M. Tice, C. Tran, J. Kostas, A. N. Alilin, J. Yin, S. Agarwal, S. A. Morris, F. H. Karzai, T. L. Lotan, W. L. Dahut, , K. Kelly
This study examines the origin and dynamics of cellular heterogeneity in different subtypes of castrate-resistant prostate cancer using patient-derived organoids and single-cell analyses, identifying distinct lineage plasticity patterns and therapeutic targets.
bioRxiv · Mar 24, 2022 · PreprintCancer Biology
A. A. Germanos, S. Arora, Y. Zheng, E. T. Goddard, I. M. Coleman, A. T. Ku, S. Wilkinson, R. A. Amezquita, M. Zager, A. Long, Y. C. Yang, J. H. Bielas, R. Gottardo, C. M. Ghajar, P. S. Nelson, , A. C. Hsieh
This study examines prostate cancer progression at single-cell resolution, identifying castration-resistant luminal cells and their role in treatment resistance and tumor heterogeneity.
bioRxiv · Mar 2, 2022Cancer Biology