Y. Fridmann-Sirkis

Stable mammalian serum albumins designed for bacterial expression

This paper designs stable mammalian serum albumins for bacterial expression, showing improved thermostability and ligand binding properties.

Functional Ambidexterity of an Ancient Nucleic Acid-Binding Domain

The paper investigates the functional robustness of the HhH protein family under chiral inversion, finding functional ambidexterity across evolutionary trajectories.

Acanthamoeba polyphaga de novo transcriptome and its dynamics during Mimivirus infection

This study generates a de novo transcriptome of Acanthamoeba polyphaga and analyzes host and virus transcriptome dynamics during Mimivirus infection, revealing cell cycle arrest and host gene modulation.

Intestinal Mucin Is a Chaperone of Multivalent Copper

The paper identifies intestinal mucin MUC2 as a copper chaperone that binds and protects against copper toxicity while enabling copper uptake.

Primordial emergence of a nucleic acid binding protein via phase separation and statistical ornithine to arginine conversion

This study demonstrates a transition from phase-separating polypeptides to dsDNA-binding proteins through statistical ornithine-to-arginine conversion and sequence duplication.