Y. Hong

This study identifies ERAD as a proteostasis checkpoint during β-selection, showing Sel1l deficiency causes ER stress and apoptosis, impairing β T cell development.

This paper develops a subunit vaccine against SARS-CoV-2 that induces sterilizing immunity in hamsters, with high neutralizing antibody titers and protection against infection and symptoms.

This study reevaluates Spinach-based RNA visualization in plants, showing potential for ex vivo and in vivo RNA monitoring.

This paper introduces ASCP, a fluorescent probe with enhanced sensitivity and specificity for detecting amyloid fibrils and oligomeric intermediates compared to ThT.

This study identifies a polybasic domain in aPKC that mediates PM targeting and kinase activity through Par-6 interaction and allosteric regulation.

This study evaluates Ripasudil's effects on pigmentary glaucoma in a porcine model, showing reduced trabecular meshwork stress fibers, restored phagocytosis, and normalized intraocular pressure.

This study identifies SIZ1-mediated SUMOylation of ROS1 as a mechanism enhancing ROS1 stability and promoting active DNA demethylation in Arabidopsis.

This paper establishes a high-throughput cell-based assay pipeline for evaluating DsbA inhibitors as antivirulence therapeutics using Escherichia coli and UPEC.

This study evaluates how different storage conditions, preservation periods, and sequencing platforms affect gut microbiome profiles using 16S rRNA gene sequencing.

This study identifies a comprehensive atlas of B-lymphocytes in triple-negative breast cancer using single-cell RNA-sequencing and antigen receptor profiling, revealing their mature characteristics and prognostic significance.

This study shows NAD+ increases antioxidant capacity in PC12 cells through SIRT2, ERK, and Nrf2 pathways under basal conditions.

This study identifies LEM-3/Ankle1 as a nuclease involved in processing meiotic recombination intermediates, promoting non-crossover (NCO) outcomes and resolving erroneous intermediates during meiotic divisions in C. elegans.

This study identifies LEM-3 as a DNA nuclease that resolves chromatin bridges during cytokinesis in C. elegans embryos, highlighting its role in genome integrity.

The paper reports multiple pepper genomes and finds that retroduplication via LTR-retrotransposons drives expansion of disease resistance genes in plants.