Y. Miyachi

Cyb5r3-based mechanism and reversal of secondary failure to sulfonylurea

This study identifies Cyb5r3 downregulation as a mechanism of sulfonylurea failure and shows that a Cyb5r3 activator can reverse this failure in an animal model.

Antagonistic epistasis of Hnf4a and FoxO1 networks through enhancer interactionsin beta-cell function

The paper investigates the antagonistic epistasis between Hnf4a and FoxO1 networks in beta-cell function through enhancer interactions and gene expression analysis.