Author

Y. Tayyar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Idris· 1 shared A. Suhrbier· 1 shared A. Supramaniam· 1 shared B. Tang· 1 shared C. Bishop· 1 shared D. Harrich· 1 shared D. Li· 1 shared D. T. Clarke· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

A. Idris

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Harnessing defective interfering particles and lipid nanoparticles for effective delivery of an anti-dengue virus RNA therapy

M.-H. Lin, P. Maniam, D. Li, B. Tang, C. Bishop, A. Suhrbier, L. Wales-Earl, Y. Tayyar, N. A. J. McMillan, L. Li, D. Harrich

This paper demonstrates that DI290-loaded lipid nanoparticles (LNP-290) effectively suppress DENV infection in cell cultures and mice, inducing IFN responses and preventing clinical signs.

bioRxiv · Apr 23, 2024Microbiology

Intranasal delivery of lipid nanoparticle encapsulated SARS-CoV-2 and RSV-targeting siRNAs reduces lung infection

A. Supramaniam, Y. Tayyar, D. T. Clarke, G. Kelly, K. V. Morris, N. A. McMillan, A. Idris

This paper develops an intranasal lipid nanoparticle (LNP) delivery system for siRNAs targeting SARS-CoV-2 and RSV, showing effective reduction of lung infection in mice.

bioRxiv · Jul 25, 2022 · PreprintMicrobiology