Author

Y. Xian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Aartse· 1 shared A. B. Ward· 1 shared A. E. Ramer-Tait· 1 shared A. H. Syeda· 1 shared A. K. Benson· 1 shared A. N. Leon· 1 shared A. Torrents de la Pena· 1 shared C. E. Cressler· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

A. Aartse

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aggresomes protect mRNA under stress in Escherichia coli

L. Pei, Y. Xian, X. Yan, C. Schaefer, A. H. Syeda, J. Howard, W. Zhang, H. Liao, F. Bai, M. C. Leake, Y. Pu

The paper shows that aggresomes in E. coli store mRNA under stress, aiding rapid recovery by protecting mRNA from degradation and facilitating translation reactivation.

bioRxiv · Apr 27, 2024Biophysics

Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines

I. del Moral-Sanchez, E. G. Wee, Y. Xian, W.-H. Lee, J. D. Allen, A. Torrents de la Pena, R. d. P. F. Rocha, J. Ferguson, A. N. Leon, S. Koekkoek, E. E. Schermer, J. A. Burger, S. Kumar, R. Zwolsman, M. Brinkkemper, , R. W. Sanders

The paper introduces a triple tandem trimer (TTT) design for HIV-1 Env and influenza HA immunogens, showing improved trimer-specific immune responses in viral vectored vaccines.

bioRxiv · Aug 27, 2023Microbiology

Establishing the phenotypic basis of adherent-invasive Escherichia coli (AIEC) pathogenicity in intestinal inflammation

H. Kittana, J. C. Gomes Neto, K. Heck, J. Sughroue, Y. Xian, S. Mantz, R. R. Segura Munoz, L. A. Cody, R. J. Schmaltz, C. L. Anderson, R. A. Moxley, J. M. Hostetter, S. C. Fernando, J. Clarke, S. D. Kachman, , A. E. Ramer-Tait

This study investigates AIEC pathogenicity in intestinal inflammation by linking in vitro phenotypes to in vivo disease severity in a murine model.

bioRxiv · Sep 18, 2019 · PreprintMicrobiology