Author

Y.-H. Chu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

E. Grotewold· 2 shared N. M. Springer· 2 shared P. Zhou· 2 shared A. Krishnan· 1 shared A. Read· 1 shared C. N. Hirsch· 1 shared C.-C. Chien· 1 shared E. E. Ellison· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPlant Biology

E. Grotewold

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Author profile →

3 papers

Recent·Most cited

Prioritizing Maize Metabolic Gene Regulators through Multi-Omic Network Integration

F. A. Gomez-Cano, J. Rodriguez, P. Zhou, Y.-H. Chu, E. L. Ellison, L. Gomez-Cano, A. Krishnan, N. M. Springer, N. de Leon, E. Grotewold

This paper develops a framework to prioritize maize metabolic gene regulators by integrating multi-omic data, identifying over 3,000 TFs and predicting new regulators of hormone, developmental, and metabolic processes.

bioRxiv · Feb 26, 2024 · PreprintPlant Biology

Hydrogen Sulfide Coordinates Glucose Metabolism Switch through Destabilizing Tetrameric Pyruvate Kinase M2

R.-H. Wang, P.-R. Chen, Y.-T. Chen, Y.-C. Chen, Y.-H. Chu, C.-C. Chien, P.-C. Chien, S.-Y. Lo, Z.-L. Wang, M.-C. Tsou, S.-Y. Chen, G.-S. Chiu, W.-L. Chen, Y.-H. Wu, L. Wang, , K.-T. Lin

This study shows hydrogen sulfide destabilizes PKM2 tetramer through sulfhydration at cysteine 326, rewiring glucose metabolism and inhibiting tumor growth.

bioRxiv · Sep 2, 2023Cancer Biology

Mutator transposon insertions within maize genes often provide a novel outward reading promoter

E. E. Ellison, P. Zhou, P. J. Hermanson, A. Read, Y.-H. Chu, C. N. Hirsch, E. Grotewold, N. M. Springer

The study identifies Mu transposon insertions in maize genes that create outward-reading promoters, leading to complex transcripts and gene expression patterns similar to wild-type.

bioRxiv · Jun 5, 2023 · PreprintPlant Biology