Author

Y.-S. Sou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Komatsu· 3 shared M. Koike· 2 shared S. Kageyama· 2 shared A. H. El-Gowily· 1 shared A. Kuma· 1 shared F. M. Omar· 1 shared N. Mizushima· 1 shared N. N. Noda· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

M. Komatsu

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Author profile →

3 papers

Recent·Most cited

Droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show slower inner fluidity

F. M. Omar, Y. Ichimura, S. Kageyama, A. H. El-Gowily, Y.-s. Sou, M. Koike, N. N. Noda, M. Komatsu

This study investigates how ALS/FTD-related p62 mutations affect liquid droplet properties, finding that some mutants show reduced Nrf2 activation and delayed turnover, while all exhibit slower inner fluidity.

bioRxiv · Jun 7, 2021Cell Biology

Autophagy controls lipid droplet formation by fine-tuning NCoR1 levels

M. Komatsu, Y.-S. Sou, M. Koike, N. Mizushima, S. Waguri, S. Terai, A. Kuma, T. Saito, S.-s. Takahashi, T. Yabe

This study shows autophagy regulates lipid droplet formation by modulating NCoR1 levels, affecting LXR target gene expression and lipid metabolism in the liver.

bioRxiv · Aug 1, 2019 · PreprintCell Biology

NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system

M. Komatsu, P. Sanchez-Martin, S. Kageyama, Y.-S. Sou

This study shows that NBR1 promotes p62-liquid droplet formation, enhancing the Keap1-Nrf2 pathway activation during oxidative stress.

bioRxiv · Jul 19, 2019Cell Biology