Author

Y.-W. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. M. Claypool· 2 shared A. D. Gregory· 1 shared A. Pandey· 1 shared C. F. Clarke· 1 shared C. Kliment· 1 shared D. N. Robinson· 1 shared D.-H. Wu· 1 shared E. S. S. Alpergin· 1 shared

Activity by Year

2019-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiochemistry

S. M. Claypool

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Author profile →

4 papers

Recent·Most cited

The mitochondrial carrier SFXN1 is critical for Complex III integrity and cellular metabolism

M. G. Acoba, E. S. S. Alpergin, S. Renuse, L. Fernandez-del-Rio, Y.-W. Lu, C. F. Clarke, A. Pandey, M. J. Wolfgang, S. M. Claypool

This study identifies SFXN1 as critical for Complex III integrity and cellular metabolism through its role in heme and central carbon metabolism, independent of its known function as a serine transporter.

bioRxiv · Jun 18, 2020Biochemistry

Adenine Nucleotide Translocase regulates the airway epithelium, mitochondrial metabolism and ciliary function

C. Kliment, J. M. K. Nguyen, M. J. Kaltreider, Y.-W. Lu, S. M. Claypool, J. E. Radder, F. C. Sciurba, Y. Zhang, A. D. Gregory, P. A. Iglesias, V. K. Sidhaye, D. N. Robinson

This study identifies Adenine Nucleotide Translocase (ANT) as a protective factor against cigarette smoke in lung cells, showing its role in mitochondrial metabolism, airway hydration, and ciliary function in COPD.

bioRxiv · May 18, 2020 · PreprintCell Biology

A transferrable and interpretable multiple instance learning model for microsatellite instability prediction based on histopathology images

Z.-Y. Dong, R. Cao, F. Yang, S.-C. Ma, L. Liu, D.-H. Wu, Y. Li, Y. Zhao, T. Wang, W.-J. Lu, W.-J. Cai, H.-B. Zhu, X.-J. Guo, Y.-W. Lu, J.-J. Kuang, , J. Yao

This paper develops a transferable and interpretable deep learning model for MSI prediction from histopathology images, achieving high AUC scores in two cohorts.

bioRxiv · Feb 29, 2020 · PreprintBioengineering

Diverse flanking sequence types of blaNDM in IncX3 and IncB/O/K/Z plasmids in Escherichia coli isolated from poultry

J. Zhu, R.-M. Cai, L.-J. Zhang, X.-R. Zheng, Y.-W. Lu, Q.-Y. Zhao, M.-X. Chang, H. Jiang

The paper identifies diverse flanking sequences of blaNDM in specific plasmids from E. coli isolated from poultry, highlighting the role of IS26 in plasmid evolution.

bioRxiv · Sep 14, 2019 · PreprintMicrobiology