Author

Yanchi Zhou

Indiana University Bloomington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Benjamin Guy BitleriD· 1 shared Heather M. O’HaganiD· 1 shared Kenneth P. NephewiD· 1 shared Lindsay W Brubaker· 1 shared Shu ZhangiD· 1 shared Tara X. MetcalfeiD· 1 shared Truc T. VuongiD· 1 shared Zhen FuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Benjamin Guy BitlerORCID

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1 paper

Recent·Most cited

Targeting MAT2A-S-adenosylmethionine (SAM) Axis Attenuates DNA Damage Response and Cancer Stemness to Increase Platinum Sensitivity in Ovarian Cancer

Shu Zhang, Zhen Fu, Yanchi Zhou, Tara X. Metcalfe, Truc T. Vuong, Lindsay W Brubaker, Benjamin Guy Bitler, Heather M. O’Hagan, Kenneth P. Nephew

Blocking MAT2A-driven SAM synthesis in ovarian cancer cells prevents cisplatin-induced DNA hypermethylation, impairs DNA repair signaling, and blocks stem cell enrichment, sensitizing MTAP-proficient and MTAP-deficient lines.

bioRxiv · Oct 13, 2026 · PreprintCancer Biology✦ In-depth digest