Author

Yanrui Zhu

Western University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:yeast· 4 Assay:DNA methylation· 2 Research Focus:genome assembly· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Christopher J. BrandliD· 4 shared Grant W. BrowniD· 4 shared Matthew D. BergiD· 4 shared Raphaël Loll‐KrippleberiD· 4 shared Julie L. Genereaux· 3 shared Bryan-Joseph San Luis· 2 shared Charles M. BooneiD· 2 shared Joshua IsaacsoniD· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMolecular Biology

Christopher J. BrandlORCID

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4 papers

Recent·Most cited

Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG

Matthew D. Berg, Yanrui Zhu, Raphaël Loll‐Krippleber, Bryan-Joseph San Luis, Julie L. Genereaux, Charles M. Boone, Judit Villén, Grant W. Brown, Christopher J. Brandl

This study shows that the impact of a mistranslating tRNA variant depends on genetic background and mistranslation frequency in yeast, with implications for understanding tRNA variants in human disease.

G3 Genes Genomes Genetics · May 19, 2022Peer-reviewedMolecular Biology

The amino acid substitution affects cellular response to mistranslation

Matthew D. Berg, Yanrui Zhu, Bianca Y. Ruiz, Raphaël Loll‐Krippleber, Joshua Isaacson, Bryan-Joseph San Luis, Julie L. Genereaux, Charles M. Boone, Judit Villén, Grant W. Brown, Christopher J. Brandl

This study compares the effects of two tRNA variants causing different amino acid substitutions in yeast, showing distinct impacts on growth, heat shock response, and transcriptome changes.

G3 Genes Genomes Genetics · Jun 26, 2021Peer-reviewedMolecular Biology

Chemical-genetic interactions with the proline analog L-azetidine-2-carboxylic acid in Saccharomyces cerevisiae

Matthew D. Berg, Yanrui Zhu, Joshua Isaacson, Julie L. Genereaux, Raphaël Loll‐Krippleber, Grant W. Brown, Christopher J. Brandl

The paper identifies genes with chemical-genetic interactions with AZC in yeast, revealing pathways involved in coping with amino acid mis-incorporation and proteotoxic stress.

G3 Genes Genomes Genetics · Oct 20, 2020Peer-reviewedGenetics

Mistranslating tRNA identifies a deleterious S213P mutation in the Saccharomyces cerevisiae eco1-1 allele

Yanrui Zhu, Matthew D. Berg, Phoebe Yang, Raphaël Loll‐Krippleber, Grant W. Brown, Christopher J. Brandl

The paper identifies a deleterious S213P mutation in the eco1-1 allele using mistranslating tRNA variants that suppress its temperature sensitivity.

Biochemistry and Cell Biology · May 30, 2020Peer-reviewedGenetics