Author

Yasaman Abdolhay

Coventry University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

David R. PoyneriD· 2 shared Farhaan Napier KhwajaiD· 2 shared Hoor AyubiD· 2 shared Mark WheatleyiD· 2 shared Dmitry B. VeprintseviD· 1 shared Ellie Thacker· 1 shared Giuseppe DeganuttiiD· 1 shared Graham LaddsiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPharmacology & Toxicology

David R. PoynerORCID

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2 papers

Recent·Most cited

PCO371 intracellular agonism at the parathyroid hormone 1 receptor produces pan-activation of signalling partners

Farhaan Napier Khwaja, Zamara Mariam, Yasaman Abdolhay, Theo Redfern-Nichols, Graham Ladds, David R. Poyner, Giuseppe Deganutti, Mark Wheatley, Hoor Ayub

This study compares the functional and structural properties of the intracellular agonist PCO371 with the extracellular peptide agonist PTH 1-34 at the PTH1R, revealing PCO371's non-biased signaling profile and lower potency.

bioRxiv · Sep 25, 2026 · PreprintPharmacology & Toxicology

Sulfo-DIBMA encapsulation uniquely preserves signalling-competent active states of class B1 GPCRs, CGRP and PTH1 receptors, in native-like nanodiscs

Farhaan Napier Khwaja, Joseph Gunner, Ellie Thacker, Yasaman Abdolhay, Richard Logan, Philip Kitchen, Dmitry B. Veprintsev, Mark Wheatley, David R. Poyner, Hoor Ayub

This paper shows that sulfo-DIBMA nanodiscs preserve active-state signaling of class B1 GPCRs better than other copolymers, enabling functional studies of these receptors.

bioRxiv · Jun 26, 2026 · PreprintPharmacology & Toxicology