Author

Yechiam Sapir

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Brian J. WaingeriD· 3 shared Daniel M. DuBreuiliD· 2 shared Aaron HeldiD· 1 shared Alexei StortchevoiiD· 1 shared Aloysius DomingoiD· 1 shared Anna‐Claire DevliniD· 1 shared Ashok RagavendraniD· 1 shared Benjamin CurralliD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersNeuroscience

Brian J. WaingerORCID

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3 papers

Recent·Most cited

A high-content platform for physiological profiling and unbiased classification of individual neurons

Daniel M. DuBreuil, Brenda M. Chiang, Kevin Zhu, Xiaofan Lai, Patrick J. Flynn, Yechiam Sapir, Brian J. Wainger

The paper introduces APPOINT, a platform for high-throughput physiological profiling of individual neurons, identifying subtypes and mechanisms of activation and drug responses.

Cell Reports Methods · Apr 2, 2021Peer-reviewedNeuroscience

A Cultured Sensorimotor Organoid Model Forms Human Neuromuscular Junctions

João D. Pereira, Daniel M. DuBreuil, Anna‐Claire Devlin, Aaron Held, Yechiam Sapir, Eugene Berezovski, James Hawrot, Katherine Dorfman, Vignesh Chander, Brian J. Wainger

The paper develops a cultured sensorimotor organoid model that forms functional neuromuscular junctions and uses it to study ALS subgroups.

bioRxiv · Mar 3, 2021 · PreprintNeuroscience

Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly

Tatsiana Aneichyk, William T. J. Hendriks, Rachita Yadav, David S. Shin, Dadi Gao, Christine A. Vaine, Ryan L. Collins, Aloysius Domingo, Benjamin Currall, Alexei Stortchevoi, Trisha Multhaupt‐Buell, Ellen B. Penney, Lilian Cruz, Jyotsna Dhakal, Harrison Brand, , Michael E. Talkowski

This study identifies the causal mechanism of X-linked Dystonia-Parkinsonism (XDP) by integrating genome and transcriptome assembly, revealing a SVA insertion causing intron retention and TAF1 dysfunction.

Cell · Jan 1, 2018Peer-reviewedGenomics