Katherine Dorfman

The paper examines chromatin states and transcription dynamics in nuclear blebs, finding variable chromatin states but consistent enrichment of transcription initiation over elongation.

The paper measures lamin B and DNA damage in blebbed nuclei to determine the effect of nuclear rupture, finding lamin B loss is rupture-dependent while DNA damage is independent.

The paper identifies plasma α-synuclein conformations that distinguish Parkinson's disease from dementia with Lewy bodies and predict cognitive decline in PD.

The paper compares lamin B and DNA levels in nuclear blebs across cell types and perturbations, finding DNA concentration is more consistently reduced than lamin B levels.

The paper develops a cultured sensorimotor organoid model that forms functional neuromuscular junctions and uses it to study ALS subgroups.

This study identifies bantam as a regulator of sleep in Drosophila by inhibiting specific wake-promoting neurons during the night.