Author

Yelda Durmus

Leiden University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Antonius P. A. JansseniD· 1 shared Bjorn R. van DoodewaerdiD· 1 shared Hans van den Elst· 1 shared Indy BroekhuizeniD· 1 shared Jana S HoffmanniD· 1 shared Mariska D. Tacoma· 1 shared Marta ArtolaiD· 1 shared Paul P. GeurinkiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Antonius P. A. JanssenORCID

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1 paper

Recent·Most cited

High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ1 riboswitch ligands

Sophie E.L. Wintermans, Jana S Hoffmann, Victor van Kuijk, Yelda Durmus, Mariska D. Tacoma, Indy Broekhuizen, Antonius P. A. Janssen, Hans van den Elst, Bjorn R. van Doodewaerd, Paul P. Geurink, Marta Artola, René C. L. Olsthoorn

This paper develops a competitive binding HTS assay to identify small molecule ligands for bacterial PreQ1 riboswitches, discovering 4 hits with activity against multiple riboswitches and one showing translation inhibition.

Nucleic Acids Research · Aug 27, 2025Peer-reviewedBiochemistry