Author

Antonius P. A. Janssen

Leiden UniversityORCID 0000-0003-4203-261XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex A. HennemaniD· 1 shared Alexandra ValeanuiD· 1 shared Alger Lazo Mori· 1 shared Andreas ToppiD· 1 shared Arne Christian RuferiD· 1 shared Berend GagesteiniD· 1 shared Bigna WörsdörferiD· 1 shared Bjorn R. van DoodewaerdiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Alex A. HennemanORCID

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2 papers

Recent·Most cited

BiochemistryNucleic Acids ResearchPeer-reviewedAug 27, 2025

High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ1 riboswitch ligands

Sophie E.L. Wintermans, Jana S Hoffmann, Victor van Kuijk…·René C. L. Olsthoorn

This paper develops a competitive binding HTS assay to identify small molecule ligands for bacterial PreQ1 riboswitches, discovering 4 hits with activity against multiple riboswitches and one showing translation inhibition.

4 citations

bacteria (other)experimental assay

𝕏 PostBluesky

Cancer BiologyMolecular & Cellular ProteomicsPeer-reviewedApr 6, 2025

CellEKT: A robust chemical proteomics workflow to profile cellular target engagement of kinase inhibitors

Joel Rüegger, Berend Gagestein, Antonius P. A. Janssen…·Mario van der Stelt

CellEKT profiles cellular target engagement of kinase inhibitors using chemical proteomics to determine IC50 values across over 300 kinases and validate results with phosphoproteomics and NanoBRET.

10 citations

humanproteomics

𝕏 PostBluesky