Steven M. Blue

This study shows KIF5A binds RNA to regulate synaptic mRNA localization and stress granules, with ALS mutations disrupting synaptic homeostasis.

This study shows LARP6 regulates fibrogenic gene translation in liver fibrosis by interacting with collagen mRNAs and reducing fibrosis in human HSCs.

The paper identifies optimal RNA base editors for RBP-RNA interaction studies by evaluating over thirty rBEs using PRINTER framework.

The paper integrates protein imaging and interaction data to create a unified map of eukaryotic cell structure, revealing new subcellular systems and protein associations.

The paper maps and characterizes RNA elements recognized by human RNA binding proteins in K562 and HepG2 cells, expanding the catalog of functional elements in the human genome.

The paper analyzes eCLIP data for 150 RBPs in K562 and HepG2 cells, revealing binding modalities, RBP functions, and novel RNA processing mechanisms.

This study identifies NIPBL's interaction with RNA and treacle in regulating pre-rRNA transcription and nucleolar organization.

RNA-targeting Cas9 reverses molecular pathology in a myotonic dystrophy mouse model by eliminating toxic CUG RNA and restoring normal cellular functions.