Author

Yoko Koseki

RIKEN Center for Integrative Medical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Haruhiko KosekiiD· 2 shared Manabu NakayamaiD· 2 shared Robert J. KloseiD· 2 shared Takashi KondoiD· 2 shared Angelika FeldmanniD· 1 shared Anne H. TurberfieldiD· 1 shared Benedikt Mathias KessleriD· 1 shared Emilia DimitrovaiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Haruhiko KosekiORCID

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2 papers

Recent·Most cited

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity

Anne H. Turberfield, Takashi Kondo, Manabu Nakayama, Yoko Koseki, Hamish W. King, Haruhiko Koseki, Robert J. Klose

This study shows KDM2 proteins repress transcription from CpG island promoters without relying on their histone demethylase activity.

Nucleic Acids Research · Jul 3, 2019Peer-reviewedMolecular Biology

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes to prime them for activation during lineage commitment

Emilia Dimitrova, Takashi Kondo, Angelika Feldmann, Manabu Nakayama, Yoko Koseki, Rebecca Konietzny, Benedikt Mathias Kessler, Haruhiko Koseki, Robert J. Klose

The paper identifies FBXL19 as a CpG island-binding protein that recruits CDK-Mediator to developmental gene promoters in mouse ES cells, priming them for activation during lineage commitment.

eLife · May 29, 2018Peer-reviewedDevelopmental Biology