Author

Nibha Mishra

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:Arabidopsis· 1

Frequent Co-Authors

Clotilde Lagier‐TourenneiD· 3 shared Albert Christian LudolphiD· 2 shared Anne‐Laurence BoutillieriD· 2 shared Gina Picchiarelli· 2 shared Laura TzeplaeffiD· 2 shared Luc DupuisiD· 2 shared Magdalini PolymenidouiD· 2 shared Pierre De RossiiD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Clotilde Lagier‐TourenneORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FUS controls muscle differentiation and structure through LLPS mediated recruitment of MEF2 and ETV5

Gina Picchiarelli, Anne Wienand, Salim Megat, Amr Aly, Marije Been, Nibha Mishra, Saskia Hutten, Erin L. Sternburg, Pierre Cauchy, Stéphane Dieterle, Marica Catinozzi, Valérie Demais, Laura Tzeplaeff, Annemarie Huebers, Dagmar Zeuschner, , Luc Dupuis

This study identifies FUS's role in muscle differentiation and structure through phase separation-mediated recruitment of ETV5 and MEF2, showing its dysfunction in FUS-ALS.

bioRxiv · Sep 18, 2024 · PreprintNeuroscience

Ribosomal protein L24 modulates mammalian microRNA processing and transfer RNA fragment production

Yonat Tzur, Serafima Dubnov, Nimrod Madrer, Adi Bar, Bettina Nadorp, Nibha Mishra, Paul A. Heppenstall, Estelle R. Bennett, David Greenberg, Katarzyna Winek, Hermona Soreq

This study identifies RPL24 as a regulator of miR processing and tRF production, showing its interaction with DDX5 and its effect on miR levels and tRF profiles in human and plant cells.

Cellular and Molecular Life Sciences · Jan 23, 2024Peer-reviewedMolecular Biology

Comprehensive preclinical evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease

Mélanie Jambeau, Kevin D. Meyer, Marián Hruška-Plocháň, Ricardos Tabet, Chao-Zong Lee, Ananya Ray-Soni, Corey Aguilar, Kitty Savage, Nibha Mishra, Nicole Cavegn, Petra Borter, Chun-Chia Lin, Karen R. Jansen‐West, Jie Jiang, Fernande Freyermuth, , Clotilde Lagier‐Tourenne

This study evaluates human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease, showing mixed effects on poly-GA levels and disease progression.

Proceedings of the National Academy of Sciences · Dec 1, 2022Peer-reviewedNeuroscience

Cytoplasmic accumulation of FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and defects in inhibitory synapses

Jelena Scekic‐Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa W. Y. Kan, Salim Megat, Pierre De Rossi, Stéphane Dieterle, Raphaelle Cassel, Marguerite Jamet, Pascal Kessler, Diana Wiesner, Laura Tzeplaeff, Valérie Demais, Sonu Sahadevan, Katharina Hembach, Hans‐Peter Müller, , Luc Dupuis

This study shows that cytoplasmic FUS mislocalization in mice causes behavioral changes and inhibitory synaptic defects without widespread neuronal loss.

Nature Communications · May 21, 2021Peer-reviewedNeuroscience