This study identifies a synergistic combination of Theobromine and Arainosine that effectively inhibits influenza virus channels, outperforming Oseltamivir against multiple strains.

Proceedings of the National Academy of Sciences · Aug 1, 2025Peer-reviewedMicrobiology

Lysine tRNA fragments and miR-194-5p co-regulate hepatic steatosis via beta-Klotho and Perilipin 2

Yonat Tzur, Katarzyna Winek, Nimrod Madrer, Serafima Dubnov, Estelle R. Bennett, David Greenberg, Geula Hanin, Asaad Gammal, Joseph Tam, Isaiah Tuvia Arkin, Iddo Paldor, Hermona Soreq

This study identifies LysTTT-5tRF and miR-194-5p as co-regulators of hepatic steatosis through beta-Klotho and Perilipin 2, showing their cooperative roles in lipid metabolism.

Molecular Metabolism · Dec 21, 2023Peer-reviewedMolecular Biology

A molecular switch for Cdc48 activity and localization during oxidative stress and aging

Meytal Radzinski, Ohad Yogev, Yarden Yesharim, Esther S. Brielle, Ran Israeli, Rosi Fassler, Naomi Melamed‐Book, Nadav Shai, Isaiah Tuvia Arkin, Elah Pick, Tommer Ravid, Maya Schuldiner, Dana Reichmann

The paper identifies a redox-sensitive site in Cdc48 that regulates its localization and activity during oxidative stress and aging in yeast.

bioRxiv · Aug 13, 2019 · PreprintMolecular Biology