Author

Yuanyuan Wang

First Affiliated Hospital of Xi'an Jiaotong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Binghui Li· 2 shared Guoguang Ying· 2 shared Miao Liu· 2 shared Yanfen Cui· 2 shared Bo Kou· 1 shared C B XuiD· 1 shared Ceshi Chen· 1 shared Changjun GuoiD· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

Binghui Li

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5 papers

Recent·Most cited

NFIC-mediated CaSR endocytosis defines a hyperactive TOMM20highCHGAhigh oxyphil cell state as a pathological driver of autonomous secondary hyperparathyroidism

Qi Yang, Junsong Liu, Yuanyuan Wang, Rong Zhao, Hexiang Li, Yao Yao, C B Xu, Bo Kou, Meng Lei, Qian Zhao, Xin Chen, Honghui Li, Ruimin Zhao, Rongrong Cui, Meichen Wang, , Peng Hou

This study identifies an NFIC-driven endo-lysosomal pathway causing CaSR downregulation in SHPT and shows HCQ can reverse this process.

bioRxiv · May 9, 2026 · PreprintCell Biology

The Hypothalamic-Pituitary-Adrenal Axis Orchestrates Energy Homeostasis during Cold Exposure

Mireia Llerins Perez, Xinran Gao, Laura Heimerl, Yuanyuan Wang, Katharina Schnabl, Uwe Firzlaff, Harald Luksch, Martin Klingenspor, Nina Henriette Uhlenhaut, Dehua Wang, Yongguo Li

This study identifies the dual role of the HPA axis in regulating energy homeostasis during cold exposure through ACTH-mediated thermogenesis and glucocorticoid-driven hyperphagia.

bioRxiv · Sep 18, 2025 · PreprintPhysiology

The genome of a vestimentiferan tubeworm (Ridgeia piscesae) provides insights into its adaptation to a deep-sea environment

Muhua Wang, Lingwei Ruan, Meng Liu, Zixuan Liu, Jian Guo He, Long Zhang, Yuanyuan Wang, Hong Shi, Mingliang Chen, Feng Yang, Runying Zeng, Jianguo He, Changjun Guo, Jianming Chen

This study reports the genome of Ridgeia piscesae, revealing that small genome size and positive selection on cell proliferation genes contribute to its high growth rates in deep-sea environments.

BMC Genomics · Feb 11, 2023Peer-reviewedGenomics

Electron transfer dictates metabolic reprogramming in proliferating cells under hypoxia

Yuanyuan Wang, Miao Liu, Yuxia Ruan, Qiaoyun Chu, Yanfen Cui, Ceshi Chen, Guoguang Ying, Binghui Li

This study shows that electron transfer dictates metabolic reprogramming in hypoxic cells by using free electron potential to predict metabolic behaviors and identify targets to inhibit tumor growth.

bioRxiv · May 19, 2018 · PreprintBiochemistry

Maintaining proton homeostasis is an essential role of glucose metabolism in cell survival

Yanfen Cui, Yuanyuan Wang, Pan Xing, Li Qiu, Miao Liu, Xin Wang, Guoguang Ying, Binghui Li

This study shows glucose metabolism maintains proton homeostasis, and its deficiency leads to lysosomal alkalinization and necrosis.

bioRxiv · Jun 13, 2016 · PreprintCancer Biology