Author
University of Central Florida
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Inês Caldeira Brás, Yuanyun Xie, Amber L. Southwell
This study investigates neuron-derived extracellular vesicles as non-invasive biomarkers for HTT protein and RNA in Huntington disease, showing subtype-specific differences in HTT levels.
Rachel Harding, Yuanyun Xie, Nicholas S. Caron…·Amber L. Southwell
This study investigates challenges in mHTT quantification in CSF, showing that absolute quantitation is unreliable due to protein complexity and recommends relative quantitation instead.
Samuel Moldenhauer, Nalini Potluri, Yuanyun Xie, Amber L. Southwell
The paper introduces a tool to automate regional brain atrophy assessment in mouse models, showing high agreement with manual methods and reduced variability.
Emily Machiela, Ritika Jeloka, Nicholas S. Caron…·Amber L. Southwell
This study investigates how aging and oxidative stress interact in Huntington disease neurons from mice and humans, finding that aging accelerates mutant HTT accumulation and increases oxidative stress sensitivity.