Identification of novel therapeutic targets for polyglutamine toxicity disorders that target mitochondrial fragmentation
Annika Traa, Emily Machiela, Paige D. Rudich, Sonja K. Soo, Megan M. Senchuk, Jeremy M. Van Raamsdonk
This study identifies novel genetic targets that reduce mitochondrial fragmentation in a C. elegans model of polyglutamine toxicity, improving movement and lifespan.
bioRxiv · Oct 19, 2021 · PreprintNeuroscience