Yubo Wang

Dark CO2 Fixation via the Ethylmalonyl-CoA Pathway Establishes Metabolic Parity: A Stoichiometric Basis for Compounding Ecosystem Shifts

The paper shows glycogen-accumulating organisms use the ethylmalonyl-CoA pathway for CO2 fixation to achieve metabolic parity with polyphosphate-accumulating organisms, leading to community shifts through stoichiometric advantages.

Autophagy activators normalize aberrant Tau proteostasis and rescue synapses in human familial Alzheimer's disease iPSC-derived cortical organoids

This study uses human iPSC-derived cortical organoids to model familial Alzheimer's disease and shows that autophagy activators reduce pathological Tau and Aβ accumulation and rescue synaptic loss.

Metabolic Segregation and Functional Gene Clusters in Anaerobic Digestion Consortia

This study reveals metabolic segregation of H2 and formate in anaerobic digestion consortia, showing their distinct roles in primary and secondary fermentation and highlighting functional gene clusters.